L-Tryptophan is an essential amino acid that serves as a precursor for the sleep hormone melatonin, for niacin and serotonin. Serotonin, an important neurotransmitter in the central nervous system, has a calming effect and plays a role in anger, aggression, mood, sleep, sexuality and appetite.‡
L-Tryptophan is the least abundant amino acid in the American diet. Even people on high protein diets generally get less than 1.5 grams daily. Supplementary L-Tryptophan provides nutritional support for restful sleep and positive mood.‡
TryptoPure® is produced by fermentation from vegetable sources, a process that yields 99%-100% pure, pharmaceutical grade L-Tryptophan. Manufactured in a pharmaceutical facility in Japan.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Take one capsule daily, typically at bedtime.
Clarinda N Sutanto, Wen Wei Loh, Jung Eun Kim, The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression, Nutrition Reviews, Volume 80, Issue 2, February 2022, Pages 306–316, https://doi.org/10.1093/nutrit/nuab027
Lindseth G, Helland B, Caspers J. The effects of dietary tryptophan on affective disorders. Arch Psychiatr Nurs. 2015 Apr;29(2):102-7. doi: 10.1016/j.apnu.2014.11.008. Epub 2014 Dec 9. PMID: 25858202; PMCID: PMC4393508.
Firk C, Markus CR. Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression. Clin Nutr. 2009 Jun;28(3):266-71. doi: 10.1016/j.clnu.2009.03.002. Epub 2009 Apr 3. PMID: 19345451.
Hogenelst K, Schoevers RA, Aan Het Rot M. The Effects of Tryptophan on Everyday Interpersonal Encounters and Social Cognitions in Individuals with a Family History of Depression. Int J Neuropsychopharmacol. 2015 Mar 2;18(8):pyv012. doi: 10.1093/ijnp/pyv012. PMID: 25733537; PMCID: PMC4571634.
Razeghi Jahromi S, Togha M, Ghorbani Z, Hekmatdoost A, Khorsha F, Rafiee P, Shirani P, Nourmohammadi M, Ansari H. The association between dietary tryptophan intake and migraine. Neurol Sci. 2019 Nov;40(11):2349-2355. doi: 10.1007/s10072-019-03984-3. Epub 2019 Jun 28. PMID: 31254181.